THE VACCINES
*
booklet
* infant schedule:
2mo Visit
12mo Visit
Boostrix
Cervarix
Daptacel
Gardasil
Hiberix
Infanrix
Kinrix
Menhibrix
Menveo
Pediarix
Pentacel
Prevnar
Trihibit
Havrix
Recombivax
Twinrix
Mercury Shots
Afluria
Fluarix
Flublok
Flulaval
Fluvirin
Fluzone
Fluvirin
MMR
ProQuad
Rotarix
Varivax
(manufacturer's list)
MMR
Pediarix
Prevnar
Recombivax
Varivax
Neuron with large Axon (single voice) top,
with multiple Dendrites (many ears) below.
top
The actual Target Germ Material in vaccines is between:
2.2 mcg - 45 mcg for dead (inactivated) microbes,
and 1,000 live viruses per species, on average.
but Target Germ Material is listed in 'mcg',
thus, 'mg' is written in 'mcg' here for proper comparison.
the MMR has 14.6 mg (14,500 mcg)
of Hydrolyzed Gelatin.
Vaccine Recipes use '%' for large amounts:
but the Target Germ Material is in 'mcg' amounts,
percentage can be turned into 'mcg' for proper comparison.
the Hep-B shot given to babies EnergixB
is 5% (25,000 mcg*) of Beer Yeast.
0.5 mL = 500,000 mcg
5% of 500,000 = 25,000 mcg.
(adult (over 7 yrs) is double that: 1.0 mL)
Hep-B, birth shot
Beer Yeast (Cerevisaie)
is genetically engineered
to "express" Hep-B virus target proteins.
ENERGIX-B description by GSK (Glaxo-Smith-Klein):
(this is what Im translating into comprehensive charts)
[Hepatitis B Vaccine (Recombinant)] is a sterile suspension of noninfectious hepatitis B virus surface antigen (HBsAg) for intramuscular administration. It contains purified surface antigen of the virus obtained by culturing genetically engineered Saccharomyces cerevisiae cells, which carry the surface antigen gene of the hepatitis B virus. The HBsAg expressed in the cells is purified by several physicochemical steps and formulated as a suspension of the antigen adsorbed on aluminum hydroxide. The procedures used to manufacture ENGERIX-B result in a product that contains no more than 5% yeast protein.
Each 0.5-mL pediatric/adolescent dose contains 10 mcg of HBsAg adsorbed on 0.25 mg aluminum as aluminum hydroxide.
Each 1-mL adult dose contains 20 mcg of HBsAg adsorbed on 0.5 mg aluminum as aluminum hydroxide.
see GSK's 'EnergixB' side effects list here
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________
The 12 month schedule adds 4 neurotropic viruses.
Babies get 7-8 doses of seperate microbes at each visit, at 2, 4, & 6 mos.
At 12 months 4 neurotropic viruses at added.
______
DEAD ("inactivated") Microbe Vaccines:
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Adacel (pertussis) = 2.5 mcg Pertussis antigens
5 Lf* Tetanus Toxoid
2 Lf Diphtheria Toxoid
3 mcg pertactin
330 mcg Aluminum
5 mcg fibriae types 2, 3(FIM)
___
*Lf = Limes Flocculation means the deadly diphtheria or tetanus toxin is bonded to antitoxin... contains the MLD (Minimum Lethal Dose) of toxin for 50 lb child, because all kids vaccines are Universal Doses,
One-Size-Fits-All for 0 - 6 yrs.
_________
Boostrix (Pertussis) = 8 mcg Pertussis antigens
5 Lf* Tetanus Toxoid
2.5 Lf Diphtheria Toxoid
390 mcg Aluminum
100 mcg polysorbate-80
100 mcg Formaldehyde
8 mcg FHA
2.5 mcg Pertactin
*Limes Flocculation, see limes, MLD
_____________________
Caterpillar Ovary Cell-lines are used to grow the HPV virus proteins
by using a tiny virus that infects bacteria, called a Bacteriophage (or simply, Phage)
to insert the virus genes into the genome of the ovary cells
so they produce virus proteins.
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Daptacel (pertussis) = 10 mcg Pertussis antigens
5 Lf* Tetanus Toxoid
15 Lf Diphtheria Toxoid
330 mcg Aluminum
5 mcg Formaldehyde
50 mcg glutaraldehyde
*Limes Flocculation, see limes, MLD
Varicella virus is a Herpes virus.
Salmonella bacteria,
the outer membrane of gram-negative bacteria is an adjuvant,
but it can cause the formation of Amyloid plaques in the brain.
One molecule of LPS (OMPC, MPL, AS01, or AS04)
triggers 100 million Fibrinogens to form into clots
that are tangled forever into Amyloids.
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Infanrix (Pertussis) = 25 mcg Pertussis antigens
10 Lf* Tetanus Toxoid
25 Lf Diphtheria Toxoid
625 mg Aluminum
25 mcg Hemagglutinin (blood-glue)
8 mcg pertactin
4,500 mcg Salt (NaCl)
100 mcg Polysorbate-80
100 mcg formaldehyde
*Limes Flocculation, see limes, MLD
_________
Kinrix (Pertussis) = 25 mcg Pertussis antigens
25 Lf* Diphtheria Toxoid
10 Lf Tetanus Toxoid
*Limes Flocculation, see limes, MLD
= 25 mcg Pertussis antigens
25 Lf* Diphtheria Toxoid
10 Lf Tetanus Toxoid
40 units** of Polio-1
8 units of Polio-2
32 units of polio-3
12.5 mcg Mercury
10 mcg Hep-B (dead virus)
850 mcg Aluminum
4,500 mcg Salt (NaCl)
25 mcg Hemagglutinin (glue)
8 mcg pertactin
*Limes Flocculation, the flocculation/coagulation of antitoxin to toxin.
= 20 mcg Pertussis antigens
5 Lf* Tetanus Toxoid
15 Lf Diphtheria Toxoid
40 units** of Polio-1
8 units of Polio-2
32 units of polio-3
42,500 mcg Sugar (sucrose)
330 mcg Aluminum
5 mcg formaldehyde.
50 mcg bovine serum albumin (blood)
20 mcg Hemagglutinin*** (glue)
5 mcg fimbriae
3 mcg pertactin (PRN)
3,300 mcg 2-phenoxyethanol
10 ppm Polysorbate-80
4 pg neomycin
4 pg polymyxin-B sulfate
*Limes Flocculation, see limes, MLD
** Antigen Units = see antigen units at Prevnar.
*** Hemagglutinin = “to Glue”: The clumping of particles, like cells, such as bacteria or red blood cells in the presence of an antibody.
The antibody or other molecule binds multiple particles and joins them, creating a large complex.
An example occurs when people are given blood transfusions of the wrong blood group.
Resident bacteria are commensals that can help the immune system or provide vitamins for their human hosts in exchange for living there. The question to be researched is "When do commensals become pathogens?" Both bacteria and viruses can become pathogenic when immune systems are stressed and down, from tramatic injury or systemic degeneration, or microbiome disbyosis from antibiotics and emulsifiers.
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TriHIBit (HIB, pertussis) = 46,800 mcg Pertussis antigens
5 Lf* Tetanus Toxoid
10,000 mcg HIB
24,000 mcg inactivated Tetanus Toxoid
6.7 Lf Diphtheria Toxoid
8.5% Sucrose
*Limes Flocculation, see limes, MLD
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Tripedia (pertussis) = 46,800 mcg Pertussis antigens (23.4 mg pertussis toxin)
5 Lf* Tetanus Toxoid
6.7 Lf Diphtheria Toxoid
170 mcg Aluminum
100,000 mcg Formaldehyde (0.02% of original amount!)
23,400 mcg Hemagglutinin (glue)
Gelatin, Polysorbate-80 (Tween-80)
*Limes Flocculation, see limes, MLD
(says, acellular pertussis vaccines are made in japan)
(mutant-Toxoid) for Gene Transfer
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Hiberix (HIB) = 10 mcg PRP HIB
30 mcg Tetanus Toxoid (not flocculated)
0.9% saline solution, lactose, & water “for injection”
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Menactra (Neisseria) = 16 mcg Neisseria bacteria
48 mcg Diphtheria Toxoid protein, mutant that is still toxic -
which is why it works, the reason its used in vaccines.
2.66 mcg formaldehyde (0.000532%… LOL)
(4 mcg each of Neisseria-A, C, Y, W-135)
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Menveo (neisseria) = 25 mcg Neisseria
32.7- 64.1 mcg CRM-197* (mutant diphtheria toxoid)
10 mcg Men-A bacteria
5 mcg Men-C bacteria
5 mcg Men-Y bacteria
5 mcg MenW-135 bacteria
____________________
Aluminum in Brands =
Adacel: 330 mcg, Boostrix: 390 mcg, Daptacel: 330 mcg, Infanrix: 625 mcg, Kinrix: 600 mcg, Pediarix: 850 mcg, PedvaxHIB: 225mcg, Pentacel: 330 mcg, Prevnar: 125ug, Tripedia: 170 mcg)
Sugar Summary (sucrose), not for flavor, but gene transfection.
Pentacel: 42,500 mcg,
FluMist Quad: 13,600 mcg,
Menhibrix: 12,600 mcg,
ACT-HIB 8.5%,
Trihibit: 8.5%)
Toxic shots can be deadly as a snake bite
without 'anti-venom' (anti-toxin)!
(antitoxin is actually antibodies against toxin)
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Havrix (Hep-A Vaccine) - grown in MRC-5 human fetus lung cells kept alive since 1961.
720 EL.U. Hep-A antigen, adsorbed onto
250 mcg Aluminum
2.5 mcg MRC-5 (human fetus cells)
25 mcg polysorbate-20
50 mcg Formalin
20 ng Neomycin
Aminoglycoside - antibiotic included in the cell growth media. Amino acids (0.3% w/v) in a phosphate-buffered saline (chloride-potassium ion for DNA transfection)
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Twinrix (Hep-A & Hep-B) -
360 Units Hep-A
20 mcg recombinant Hep-B (genetically altered)
225 mcg Aluminum
1.25 mcg MRC-5 cellular proteins (human fetus lung cells, kept alive since 1961)
amino acids, sodium chloride, phosphate buffer,
20 ng Neomycin (aminoglycoside antibiotic),
1) Hep-A Virus is grown in MRC-5 human fetus cells.
2) Hep-B Virus is genetically engineered Yeast cells with Hep-B antigens.
Each antigen is adsorbed separately onto aluminum.
_________
Vaqta – Hep-A virus grown in MRC-5 human fetal cell line.
25 Units hepatitis A virus antigen
225 mcg aluminum
35 mcg of sodium borate
0.9% salt (NaCl)
0.05 mcg of nonviral protein
2,000,000 mcg DNA (human fetus DNA from MRC-5 cell-line)
5,000 mcg Bovine Albumin (cow-blood) (10–4)
0.8 mcg Formaldehyde
FLU Shots (DEAD virus)
(only nasal spray is LIVE virus)
A Virus, just a bundle of genes
with a delivery system.
_
Molecule of Mercury annihilating a budding Dendrite
footage by Univ of Calgary (canada)
"How mercury causes brain neuron damage"
Flu Shots use MERCURY:
1) Mercury is used in multi-dose vials, which today are 10 dose vials.
2) Multi-dose vials of Fluzone have 500 mcg thimerosal which is 50% mercury (10 doses in single 5mL vial) giving 25 mcg mercury per individual (0.5 dose) starting at 6 months.
The multi-dose 5mL vial containing ten 0.5mL individual doses.
Mercury is added to keep bacteria from growing
after each syringe fills up from the vial.
(all multi-dose vials for any vaccine must use mercury)
Afluria
45 mcg total (15 mcg each strain):
H1N1 virus (2010, California),
H3N2 virus (2012, Texas),
BX-51B virus (2012, Massachusetts)
24.5 mcg Mercury
4,100 mcg Salt
80 mcg potassium phosphate (monobasic)
20 mcg potassium choride
300 mcg sodium phosphate (dibasic)
80 mcg sodium phosphate (monobasic)
1.5 mcg Calcium Chloride
10 ppm sodium taurodeoxycholate
1 mcg Ovalbumin
3 ng neomycin sulfate
Quote: “Following harvest... the virus particles are disrupted
using sodium taurodeoxycholate to produce a split virion.
The “disrupted” virus is further suspended
in a phosphate buffered isotonic solution.
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Fluarix
45 mcg total (15 mcg each):
H1N1 virus (2010, California),
H3N2 virus (2012, Texas),
BX-51B virus (2012, Massachusetts)
85 mcg TRITON X-100 (industrial detergent)
415 mcg Polysorbate (Tween-80)
0.0016 mcg Hydrocortisone (residual)
0.15 mcg gentamicin sulfate
0.05 mcg Ovalbumin
5 mcg Formaldehyde
100 mcg Hydrogen Succinate (a-tocopheryl)
50 mcg sodium deoxycholate (“inactivates” virus)
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FluBlok
45 mcg H1N1 virus (Christchurch/2010) (an A/California/7/2009-like virus)
45 mcg H3N2 virus (Victoria/2011)
45 mcg BX-39 virus (Wisconsin/2010)
38.5 mcg Baculo-Virus*, host cell proteins, cellular DNA
100 mcg Triton X-100
4,400 mcg Salt
1,495 mcg Sodium Phosphate
27.5 mcg Polysorbate 20 (Tween-20)
*Baculo-Virus, see Baculo-Virus,(a nuclear polyhedrosis virus)
Insect Cell-line (continuous)= Fall Army-Worm “Spodoptera Frugiperda”
Quote, manufacturers notes:
It contains purified HA proteins produced in a continuous insect cell line (expresSF+®)
that is derived from Sf9 cells of the fall armyworm, Spodoptera frugiperda,
and grown in serum-free medium composed of chemically-defined
lipids, vitamins, amino acids, and mineral salts.
Each of the three HAs (hemagglutinin, Antigens fr cell membranes) is expressed in this cell line
using a baculovirus vector
(Autographa californica nuclear polyhedrosis virus),
extracted from the cells with Triton X-100
and further purified by column chromatography.
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Flulaval
15 mcg H1N1 virus (California/2009)
15 mcg H3N2 virus (Texas/2012)
15 mcg BX-51B virus (Massachusetts/2012)
25 mcg Mercury
0.3 mcg Ovalbumin
25 mcg Formaldehyde
50 mcg Sodium Deoxycholate
240 mcg a-tocopheryl hydrogen succinate
665 mcg Polysorbate-80
*includes 50 mcg mercury from thimerosal.
full text: H1N1 virus (A/California/7/2009 NYMC X-179A)
H3N2 virus (A/Texas/50/2012 NYMC X-223A)
BX-51B virus (B/Massachusetts/2/2012 NYMC)
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Fluvirin
45 mcg total of 15 each:
H1N1 virus (Christchurch/2010) (an A/California/7/2009-like virus)
H3N2 virus (Texas/2012)
BX-51B virus(Massachusetts/2012)
25 mcg Mercury
150 ppm of Nonylphenol Ethoxylate*.
< 25 mcg mercury from 50 mcg thimerosal.
3.75 mcg Polymyxin
2.5 mcg neomycin
0.5 mcg betapropiolactone
1 mcg ovalbumin (egg proteins)
*Nonylphenol Ethoxylate is a phenol, which only 1,000 ppm is lethal to humans in only 5 mins.
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FluZone
0 - 6 yrs (childrens shot)
(powerpoint page from booklet)
H1N1 virus (California/2009)
H3H2 virus (Texas/2012)
BX-51B virus(Massachusetts/2012)
25 mcg Mercury
Sodium Phosphate-buffered isotonic Sodium Chloride
<100 mcg Formaldehyde
<150 mcg Octylphenol Ethoxylate (300 ppm)
0.05% or 250 mcg Hydrolyzed Gelatin (an Excito-toxin).
The “Embryonated” egg (with FULL fetus)
is used to grow the 15 mcg of each flu strain in every flu shot.
It takes 3 chicken embryos to produce
the 45 mcg total in each Flu Shot (3 strains),,br> which are ground up inside their eggs.
measles virus giving birth,br> genetic pro-generation.
Live Virus Vaccines
Many are neurotropic viruses that can get into young brains, CNS, ENS,
or the immune response is the damaging factor,
compounded by multi-doses of other live neurotropic viruses
that force the immune compromises,
creates exhaustion, and cascading malfunctions.
Counting Virus in Vaccines, reflection of infection power =
CCID - Cell-Culture-Infective-Dose
FFU – Florescent Focus Units (influenza)
PFU – Plaque-Forming Units (varicella/chicken pox)
TCID - Tissue Culture Infectious Dose (measles, mumps, rubella)
(TCID50 virus kills 50% of infected cells)
IU - Infectious Units (rotavirus)
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MMR-II (Measles, Mumps, Rubella)
1,000 TCID50 Measles Virus
12,500 TCID50 Mumps Virus
1,000 TCID50 Rubella Virus
14,500 mcg Sorbitol (corn-syrup sugar)
1,900 mcg Sugar Sucrose
14,500 mcg Gelatin
<300 mcg Recombinant Human Albumin (human blood DNA)
<1 ppm Fetal Bovine Serum (blood)
25 mcg of neomycin <
Sodium chloride
Measles Virus... Measles budding from host cell.
MMR shot contains 3 live neurotropic viruses.
The immune system cannot give equal attention to each one equally.
Live Varicella (chicken pox) virus is given at the same time.
Varicella is a Herpes virus and will move into spinal ganglia forever.
The immune system has to contend with measles, mumps, and a rubella virus that's temperature-sensitive (ts virus) that only stops replicating above 37C (98.6F) & 39C (102.2F),
*normal body temperature is actually 98.2F not 98.6F and varies during the time of day and between genders.
see article "Normal Body Temperature: Rethinking the normal human body temperature" = Harvard article
Our findings conflicted with Wunderlich's
in that 36.8°C (98.2°F) rather than 37.0°C (98.6°F)
was the mean oral temperature of our subjects;
37.7°C (99.9°F) rather than 38.0°C (100.4°F)
was the upper limit of the normal temperature range;
maximum temperatures, like mean temperatures, varied with time of day;
and men and women exhibited comparable thermal variability.
Wunderlich's original thermometer
is over 12 inches long,
it was stuck under the armpit
incorrectly measuring body temperature
(*proved to be closer to 98.2 than 98.6)
ts viruses mean they replicate until fever shuts them down at 102.2 F for the two strains of Type-A rubella virus, and 98.6 F for two strains of Type-B rubella virus.
Description by Merck
M-M-R® II (MEASLES, MUMPS, and RUBELLA VIRUS VACCINE LIVE) DESCRIPTION M-M-R® II (Measles, Mumps, and Rubella Virus Vaccine Live) is a live virus vaccine for vaccination against measles (rubeola), mumps, and rubella (German measles). M-M-R II is a sterile lyophilized preparation of (1) ATTENUVAX® (Measles Virus Vaccine Live), a more attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture; (2) MUMPSVAX® (Mumps Virus Vaccine Live), the Jeryl Lynn™ (B level) strain of mumps virus propagated in chick embryo cell culture; and (3) MERUVAX® II (Rubella Virus Vaccine Live), the Wistar RA 27/3 strain of live attenuated rubella virus propagated in WI-38 human diploid lung fibroblasts.{1,2} The growth medium for measles and mumps is Medium 199 (a buffered salt solution containing vitamins and amino acids and supplemented with fetal bovine serum) containing SPGA (sucrose, phosphate, glutamate, and recombinant human albumin) as stabilizer and neomycin. The growth medium for rubella is Minimum Essential Medium (MEM) [a buffered salt solution containing vitamins and amino acids and supplemented with fetal bovine serum] containing recombinant human albumin and neomycin. Sorbitol and hydrolyzed gelatin stabilizer are added to the individual virus harvests.
MMR vaccine 10-pack of
0.5 mL dose vials, with diluent.
ProQuad (Measles, Mumps, Rubella, Varicella) =
3.00 log10 TCID50 of measles virus
4.30 log10 TCID50 of mumps virus
3.00 log10 TCID50 of rubella virus
3.99 log10 PFU of Oka/Merck varicella virus
21,000 mcg Sugar
16,000 mcg Sorbitol (corn-syrup sugar)
11,000 mcg Gelatin
250 mcg Human Albumin (blood)
2,500 mcg Urea
2,300 mcg Sodium Chloride
380 mcg Monosodium Glutamate
140 mcg Sodium Phosphate
130 mcg Sodium bicarbonate
94,000 mcg Potassium Phosphate
58,000 mcg Potassium chloride
500 mcg Bovine Serum Albumin (cow-blood)
MRC-5** cells (human fetal cell-line) including its DNA and protein.
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Rotarix (Rotavirus) -
< 500,000 CCID-50 of Rotavirus (G1-P8)
Dextran (sugar)
Dulbecco’s modified Eagle medium, amino acids,
sorbitol
sucrose
Quote: Fecal shedding of rotavirus after one dose was detected in 50% to 80% of infants at day 7.
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Varivax (varicella/chicken pox) –
PFU means "Plaque-Forming-Units" (cells patch up the hole left by invading viruses with plaque, to count viruses).
1,350 PFU Varicella virus
25,000 mcg Sugar
12,500 mcg Gelatin
3,200 mcg Salt
450 mcg sodium phosphate dibasic
80 mcg potassium chloride
500 mcg monosodium glutamate
DNA from MRC-5 cell-line (human fetus**)
DNA from WI-38 cell-line (human fetus)
DNA from Guinea Pigs
Fetal Bovine serum (cow fetus blood)
a) the strain with the power of 1350 PFU was initially obtained from a child with ‘wild-type varicella,
b) then grown in Human Embryonic lung cells (MRC-5),
c) then grown in Embryonic Guinea Pig cells,
d) then grown in Human embryonic lung cells (WI-38),
e) Further passage of the virus was in human fetus lung cells (MRC-5).
Note: The virus was initially obtained from a child with wild-type varicella,
then introduced into human embryonic lung cell cultures,
propagated in embryonic guinea pig cells
and finally propagated in human diploid cell cultures (WI-38).
Further passage of the virus for varicella vaccine
was performed at Merck Research Laboratories (MRL)
in human diploid cell cultures (MRC-5).
Live Varicella (chicken pox) stays forever.
(this is what I translate into graphs)
VARIVAX [Varicella Virus Vaccine Live (Oka/Merck)] is a preparation of the Oka/Merck strain of live, attenuated varicella virus. The virus was initially obtained from a VA with natural varicella, then introduced into human embryonic lung cell cultures, adapted to and propagated in embryonic guinea pig cell cultures and finally propagated in human diploid cell cultures (WI-38). Further passage of the virus for varicella vaccine was performed at Merck Research Laboratories (MRL) in human diploid cell cultures (MRC-5) that were free of adventitious agents.
This live, attenuated varicella vaccine is a lyophilized preparation containing sucrose, phosphate, glutamate, and processed gelatin as stabilizers.
VARIVAX (varicella virus vaccine live) , when reconstituted as directed, is a sterile preparation for subcutaneous administration. Each 0.5 mL dose contains the following: a minimum of 1350 PFU (plaque forming units) of Oka/Merck varicella virus when reconstituted.
FluMist Quadrivalent = 106.5-7.5 FFU (florescent focus units) each
Live attenuated influenza virus Re-Assortments of each strain:
H1N1 (California/2009)
H3H2 (Texas/2012)
BX-51B (Massachusetts/2012)
B/Brisbane/60/2008-like virus
188 mcg Monosodium Glutamate
13,540 mcg Sucrose (table sugar)
3,220 mcg Potassium Phosphate
2,420 mcg Arginine
2,000 mcg hydrolyzed Porcine Gelatin
0.24 mcg Ovalbumin
0.37 mcg Ethylene-diamine-tera-acetic acid (EDTA)
Full text: A/California/7/2009 (H1N1)
A/Texas/50/2012 (H3N2) (an A/Victoria/361/2011-like virus)
B/Massachusetts/2/2012 (B/Yamagata/16/88 lineage)
B/Brisbane/60/2008 (B/Victoria/2/87 lineage)
Other Vaccines
Fendrix
The new Hep-B vaccine (FENDRIX, used in Europe 2016) forces a greater immune response
by adding Salmonella LPS.
[Hepatitis B Vaccine (Recombinant)] is a sterile suspension of noninfectious hepatitis B virus surface antigen (HBsAg) for intramuscular administration. It contains purified surface antigen of the virus obtained by culturing genetically engineered Saccharomyces cerevisiae cells, which carry the surface antigen gene of the hepatitis B virus. The HBsAg expressed in the cells is purified by several physicochemical steps and formulated as a suspension of the antigen adsorbed on aluminum hydroxide. The procedures used to manufacture ENGERIX-B result in a product that contains no more than 5% yeast protein.
Each 0.5-mL pediatric/adolescent dose contains 10 mcg of HBsAg adsorbed on 0.25 mg aluminum as aluminum hydroxide.
Each 1-mL adult dose contains 20 mcg of HBsAg adsorbed on 0.5 mg aluminum as aluminum hydroxide.
Side Effects listed by Manufacturers
(mostly, Merck & GSK)
& can happen again...
_
ENERGIX-B side effects (Glaxo-Smith-Kline)
Infections and Infestations: Upper respiratory tract illnesses.
Blood and Lymphatic System Disorders: Lymphadenopathy.
Metabolism and Nutrition Disorders: Anorexia.
Psychiatric Disorders: Agitation, insomnia.
Nervous System Disorders: Somnolence, tingling.
Vascular Disorders: Flushing, hypotension.
Gastrointestinal Disorders: Abdominal pain/cramps, constipation, diarrhea, nausea, vomiting.
Skin and Subcutaneous Tissue Disorders: Erythema, petechiae, pruritus, rash, sweating, urticaria.
Musculoskeletal and Connective Tissue Disorders: Arthralgia, back pain, myalgia, pain/stiffness in arm, shoulder, or neck.
General Disorders and Administration Site Conditions: Chills, influenza-like symptoms, injection site ecchymosis, injection site pain, injection site pruritus, irritability, malaise, weakness.
Infections and Infestations: Herpes zoster, meningitis.
Blood and Lymphatic System Disorders: Thrombocytopenia.
Immune System Disorders: Allergic reaction, anaphylactoid reaction, anaphylaxis.
An apparent hypersensitivity syndrome (serum sickness-like) of delayed onset has been reported days to weeks after vaccination, including: arthralgia/arthritis (usually transient), fever, and dermatologic reactions such as urticaria, erythema multiforme, ecchymoses, and erythema nodosum.
Nervous System Disorders: Encephalitis, encephalopathy, migraine, multiple sclerosis, neuritis, neuropathy including hypoesthesia, paresthesia, Guillain-Barre syndrome and Bell's palsy, optic neuritis, paralysis, paresis, seizures, syncope, transverse myelitis.
Eye Disorders: Conjunctivitis, keratitis, visual disturbances.
Ear and Labyrinth Disorders: Earache, tinnitus, vertigo.
Cardiac Disorders: Palpitations, tachycardia.
Vascular Disorders: Vasculitis.
Respiratory, Thoracic, and Mediastinal Disorders: Apnea, bronchospasm including asthma-like symptoms.
Gastrointestinal Disorders: Dyspepsia.
Skin and Subcutaneous Tissue Disorders: Alopecia, angioedema, eczema, erythema multiforme including Stevens-Johnson syndrome, erythema nodosum, lichen planus, purpura.
Musculoskeletal and Connective Tissue Disorders: Arthritis, muscular weakness.
Investigations: Abnormal liver function tests.
_
MMR-II side effects (Merck)
ADVERSE REACTIONS in current MMR (listed by Merck):
Body as a Whole: Panniculitis; atypical measles; fever; syncope; headache; dizziness; malaise; irritability.
Cardiovascular System: Vasculitis.
Digestive System: Pancreatitis; diarrhea;vomiting; parotitis; nausea.
Endocrine System: Diabetes mellitus.
Hemic and Lymphatic System: Thrombocytopenia; purpura; regional lymphadenopathy; leukocytosis.
&nsbp; (7 Immune System Anaphylaxis and anaphylactoid reactions; angioneurotic edema (including peripheral or facial edema) and bronchial spasm).
Musculoskeletal System: Arthritis; arthralgia; myalgia; Arthralgia and/or arthritis (usually transient and rarely chronic), and polyneuritis.
Nervous System: Encephalitis; encephalopathy; measles inclusion body encephalitis (MIBE); subacute sclerosing panencephalitis (SSPE); Guillain-Barré Syndrome (GBS); acute disseminated encephalomyelitis (ADEM); transverse myelitis; febrile convulsions; afebrile convulsions or seizures; ataxia; polyneuritis; polyneuropathy; ocular palsies; paresthesia.
Respiratory System: Pneumonia; pneumonitis; sore throat; cough; rhinitis.
Skin: Stevens-Johnson syndrome; erythema multiforme; urticaria; rash; measles-like rash; pruritis.
Local reactions: burning/stinging at injection site; wheal and flare; redness (erythema); swelling; induration; tenderness; vesiculation at injection site; Henoch-Schönlein purpura; acute hemorrhagic edema of infancy.
8 Special Senses — Ear Nerve deafness; otitis media.
Special Senses — Eye Retinitis; optic neuritis; papillitis; retrobulbar neuritis; conjunctivitis.
Urogenital System: Epididymitis; orchitis.
Other: Death from various, and in some cases unknown, causes has been reported.
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PEDIARIX side effects (Glaxo-Smith-Kline)
Deaths and seizures. (GSK danced past this after mere mention)
Cardiac Disorders: Cyanosis.
Gastrointestinal Disorders: Diarrhea, vomiting.
General Disorders: Fatigue, injection site cellulitis, injection site induration, injection site itching, injection site nodule/lump, injection site reaction, injection site vesicles, injection site warmth, limb pain, limb swelling.
Immune System Disorders: Anaphylactic reaction, anaphylactoid reaction, hypersensitivity.
Infections and Infestations: Upper respiratory tract infection.
Investigations: Abnormal liver function tests.
Nervous System Disorders: Bulging fontanelle, depressed level of consciousness, encephalitis, hypotonia, hypotonic-hyporesponsive episode, lethargy, somnolence, syncope.
Psychiatric Disorders: Crying, insomnia, nervousness, restlessness, screaming, unusual crying.
Respiratory, Thoracic, and Mediastinal Disorders: Apnea, cough, dyspnea.
Skin and Subcutaneous Tissue Disorders: Angioedema, erythema, rash, urticaria.
Vascular Disorders: Pallor, petechiae.
Blood and Lymphatic System Disorders: Idiopathic thrombocytopenic purpura, lymphadenopathy, thrombocytopenia.
Gastrointestinal Disorders: Abdominal pain, intussusception, nausea.
General Disorders and Administration Site Conditions: Asthenia, malaise.
Hepatobiliary Disorders: Jaundice.
Immune System Disorders: Anaphylactic shock, serum sickness-like disease.
Musculoskeletal and Connective Tissue Disorders: Arthralgia, arthritis, muscular weaknessb, myalgia.
Nervous System Disorders: Encephalopathy, headache, meningitis, neuritis, neuropathy, paralysis.
Skin and Subcutaneous Tissue Disorders: Alopecia, erythema multiforme, lichen planus, pruritusa, Stevens Johnson syndrome.
Vascular Disorders: Vasculitis.
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PREVNAR side effects (pfizer):
Administration site conditions: Vaccination-site dermatitis, vaccination-site pruritus, vaccination-site urticaria.
Blood and lymphatic system disorders: Lymphadenopathy localized to the region of the injection site.
Cardiac Disorders: Cyanosis.
Immune system disorders: Anaphylactic/anaphylactoid reaction including shock Nervous System Disorders: Hypotonia.
Skin and subcutaneous tissue disorders: Angioneurotic edema, erythema multiforme Respiratory: Apnea.
Vascular Disorders: Pallor.
Allergic Reactions: hives; difficulty breathing; swelling of the face, lips, tongue, or throat.
Serious side effects such as: high fever (103 degrees or higher); seizure (convulsions); wheezing, trouble breathing; severe stomach pain, severe vomiting or diarrhea; easy bruising or bleeding; or severe pain, itching, irritation, or skin changes where the shot was given.
Less serious side effects include: crying, fussiness; headache, tired feeling; muscle or joint pain; drowsiness, sleeping more or less than usual; mild redness, swelling, tenderness, or a hard lump where the shot was given; loss of appetite, mild vomiting or diarrhea; low fever (102 degrees or less), chills; or mild skin rash.
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Serious adverse events reported following vaccination in infants and toddlers occurred in 8.2% among Prevnar 13 recipients and 7.2% among Prevnar recipients.
The most commonly reported serious adverse events were in the 'Infections and infestations' system organ class including bronchiolitis (0.9%, 1.1%), gastroenteritis, (0.9%, 0.9%), and pneumonia (0.9%, 0.5%) for Prevnar 13 and Prevnar respectively, and deaths, all as a result of sudden infant death syndrome (SIDS). These SIDS rates are consistent with published age specific background rates of SIDS from the year 2000.
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Prevnar 13 Side Effects in adults: fatigue, tired feeling, headache, muscle pain, joint pain, injection site reactions (pain, redness, swelling, tenderness, or a hard lump), limitation of arm movement, chills, skin rash, tired feeling, drowsiness, sleeping more or less than usual, vomiting, diarrhea, or low grade fever (102 degrees or less).
In infants and toddlers, common side effects of Prevnar 13 include the above, and: crying, fussiness, irritability.
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ReCOMBIVAX side effects (Merck)
The most frequent systemic complaints include fatigue/weakness; headache; fever (= 100°F); malaise.
Gastrointestinal Disorders: Nausea; diarrhea.
Respiratory, Thoracic And Mediastinal Disorders: Pharyngitis; upper respiratory infection.
General Disorders: Sweating; achiness; sensation of warmth; lightheadedness; chills; flushing.
Gastrointestinal Disorders: Vomiting; abdominal pains/cramps; dyspepsia; diminished appetite.
Respiratory, Thoracic And Mediastinal Disorders: Rhinitis; influenza; cough.
Nervous System Disorder: Vertigo/dizziness; paresthesia 5.
Skin And Subcutaneous Tissue Disorders: Pruritus; rash; angioedema; urticaria.
Musculoskeletal And Connective Tissue Disorders: Arthralgia including monoarticular; myalgia; back pain; neck pain; shoulder pain; neck stiffness.
Blood And Lymphatic Disorders: Lymphadenopathy.
Psychiatric Disorders: Insomnia/disturbed sleep.
Ear And Labyrinth Disorders: Earache.
Renal And Urinary Disorders: Dysuria.
Cardiac Disorders: Hypotension.
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VARIVAX side effects (Merck)
Adverse events reported: upper respiratory illness, headache, fatigue, cough, myalgia, disturbed sleep, nausea, malaise, diarrhea, stiff neck, irritability/nervousness, lymphadenopathy, chills, eye complaints, abdominal pain, loss of appetite, arthralgia, otitis, itching, vomiting, other rashes, constipation, lower respiratory illness, allergic reactions (including allergic rash, hives), contact rash, cold/canker sore.
Body as a Whole: Anaphylaxis (including anaphylactic shock) and related phenomena such as angioneurotic edema, facial edema, and peripheral edema.
Eye Disorders: Necrotizing retinitis (in immunocompromised individuals).
Hemic and Lymphatic System: Aplastic anemia; thrombocytopenia (including idiopathic thrombocytopenic purpura (ITP)).
Infections and Infestations: Varicella (vaccine strain).
Nervous/Psychiatric: Encephalitis; cerebrovascular accident; transverse myelitis; Guillain-Barré syndrome; Bell's palsy; ataxia; non-febrile seizures; aseptic meningitis; dizziness; paresthesia.
Respiratory: Pharyngitis; pneumonia/pneumonitis.
Skin: Stevens-Johnson syndrome; erythema multiforme; Henoch-Schönlein purpura; secondary bacterial infections of skin and soft tissue, including impetigo and cellulitis; herpes zoster.
Micro-carrier-beads covered with fetal monkey kidney cells
used by viruses to multiply for vaccines.
Introductory Reference
Kain, Bigtree, Jones, Shuman, Wakefield, Silvers.
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